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Hangzhou Royall Import & Export Co., Ltd.

Ruxolitinib, 941678-49-5, Good Quality manufacturer / supplier in China, offering Good Quality, Low Price, Made in China, 99% Ruxolitinib CAS: 941678-49-5, 1300 Model Slitting Machine for Cardboard, Good Transversely Cutting Machine of The Corrugated Paperboard (MJNC-2) and so on.

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Supplier Homepage Product API & Intermediates & Custom synthesis Good Quality, Low Price, Made in China, 99% Ruxolitinib CAS: 941678-49-5

Good Quality, Low Price, Made in China, 99% Ruxolitinib CAS: 941678-49-5

FOB Price: US $1 / Piece
Min. Order: 1 Piece
Min. Order FOB Price
1 Piece US $1/ Piece
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Production Capacity: 3kg/Month
Transport Package: Aluminum Oil Bag
Payment Terms: L/C, T/T, D/P, Paypal, Money Gram, Western Union

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Basic Info
  • Model NO.: 941678-49-5
  • Customized: Non-Customized
  • State: Solid
  • Product Name: Ruxolitinib
  • Mf: C17h18n6
  • Specification: 99%
  • Powder: Yes
  • Suitable for: Elderly, Children, Adult
  • Purity: >99%
  • CAS: 941678-49-5
  • Trademark: ROYAL PHARM
  • Origin: China
Product Description


Ruxolitinib (INC424, INCB18424, trade names Jakafi and Jakavi, by Incyte Pharmaceuticals and Novartis) is a drug for the treatment of intermediate or high-risk myelofibrosis, a type of myeloproliferative disorder that affects the bone marrow.
It is also being investigated for the treatment of other types of cancer (such as lymphomas and pancreatic cancer),for polycythemia vera, for plaque psoriasis, and for alopecia areata.
Ruxolitinib is a Janus kinase inhibitor with selectivity for subtypes JAK1 and JAK2 of this enzyme. Ruxolitinib inhibits dysregulated JAK signaling associated with myelofibrosis. JAK1 and JAK2 recruit signal transducers and activators of transcription (STATs) to cytokine receptors leading to modulation of gene expression.


Ruxolitinib

Ruxolitinib;(R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;(betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile;1H-Pyrazole-1-propanenitrile,.beta.-cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-,(.beta.R)-;(3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile;(3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile;INCB018424 (Ruxolitinib);Jakafi
CAS:941678-49-5

C17H18N6

306.371

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